diff --git a/Source/Engine/UI/GUI/Tooltip.cs b/Source/Engine/UI/GUI/Tooltip.cs
index ea3c27658..31429ec3c 100644
--- a/Source/Engine/UI/GUI/Tooltip.cs
+++ b/Source/Engine/UI/GUI/Tooltip.cs
@@ -242,6 +242,12 @@ namespace FlaxEngine.GUI
                 if (_window)
                     _window.Position = mousePos + TooltipOffset;
             }
+            
+            if (Input.Mouse.IsAnyButtonDown || Math.Abs(Input.Mouse.ScrollDelta) > Mathf.Epsilon)
+            {
+                // Hide popup when buttons are pressed
+                Hide();
+            }
 
             base.Update(deltaTime);
         }